Publications

Selected papers and research artifacts with direct access to paper, preprint, code, and archived releases.

2026

Guiding Peptide Kinetics via Collective-Variable Tuning of Free-Energy Barriers

Alexander Zhilkin, Muralika Medaparambath, Dan Mendels

Journal of Chemical Theory and Computation, recent paper

Introduces a framework for rationally modifying free-energy surfaces to control conformational transition rates, using HLDA-based collective variables derived from limited metastable-state sampling.

2025

Enhancing Bayesian Network Discovery by Sampling Markov Equivalent DAGs

Alexander Zhilkin

Master's thesis, University of Helsinki, Master's thesis

Introduces a Markov Equivalent Step for Bayesian network structure discovery MCMC, improving convergence and exploration of complex network-structure posteriors.

Scaling Up Bayesian DAG Sampling

Daniele Nikzad, Alexander Zhilkin, Juha Harviainen, Jack Kuipers, Giusi Moffa, Mikko Koivisto

arXiv preprint

Presents more efficient Bayesian DAG sampling methods, including faster basic graph moves and approximate parent-set pruning to improve scalability.